Gliotoxin
作者：齐岳
发布时间：2023-08-30
09:00:20
点击数：
产品名称：Gliotoxin
产品描述：
| 结构类型 | 天然产物 > 其他 |
| 产品描述 | Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway. Gliotoxin is a mycotoxin produced by several moulds such as Aspergillus fumigatus. Gliotoxin activates PKA and increases intracellular cAMP concentration and inhibits inducible NF-κB activity by preventing IκB degradation, which consequently induces host-cell apoptosis. |
| 靶点活性 | Mycobacterium tuberculosis:<0.03 μM(MIC50) |
| 体外活性 | The structures of these compounds (1-12) were determined mainly by the extensive NMR, ESIMS spectra data and by comparison with previously described compounds. Besides, anti-tuberculosis, cytotoxic, antibacterial, COX-2 inhibitory and antiviral activities of these compounds were evaluated[1] |
| 分子量 | 326.39 |
| 分子式 | C13H14N2O4S2 |
| CAS No. | 67-99-2 |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
Chloroform: 10 mg/mL
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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西安齐岳生物科技有限公司是集化学科研和定制与一体的高科技化学公司。业务范围包括化学试剂和产品的研发、生产、销售等。涉及产品为通用试剂的分销、非通用试剂的定制与研发，涵盖生物科技、化学品、中间体和化工材料等领域。
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