Gypsogenin
作者：齐岳
发布时间：2023-08-23
09:21:27
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产品名称：Gypsogenin
产品描述：
| 结构类型 | 天然产物 > 多糖和糖苷 |
| 产品描述 | Gypsogenin is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities. |
| 体外活性 | Gypsogenin (1) was obtained by acidic hydrolysis from its saponin.?While the parent compound 1 acted as a selective inhibitor for butyrylcholinesterase (from equus) possessing a moderate mixed-type inhibition of the enzyme, Ki values as low as 2.67 0.59 μM were determined for (3β,4α) 3-O-acetyl-olean-12-ene-23,28-dinitrile (11) and acetylcholinesterase (AChE, from electric eel).?Thus, 11 possesses one-fifth of the inhibitory activity of the "gold standard" galantamine hydrobromide;?this compound is one of the first pentacyclic triterpenoids described as a potent AChE-selective inhibitor |
| 别名 | 丝石竹皂苷元, 639-14-5 |
| 分子量 | 470.68 |
| 分子式 | C30H46O4 |
| CAS No. | 639-14-5 |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 27.5 mg/ml (58.42 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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