Sugiol
作者：齐岳
发布时间：2023-09-06
09:05:34
点击数：
产品名称：Sugiol
产品描述：
| 结构类型 | 天然产物 > 萜类 |
| 产品描述 | Sugiol has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. Sugiol's efficacy in inhibiting the inflammatory cytokines of IL-1beta and TNF-alpha could be attributed to a reduction of the ROS that leads to a decrease in the phosphorylation of MAPKs. |
| 体外活性 | An abietane type diterpenoid Sugiol, isolated from ethyl acetate extract of M. glyptostroboides cones, was analyzed for its antioxidant efficacy as reducing power ability and lipid peroxidation inhibition as well as its ability to scavenge free radicals such as 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl radicals. The Sugiol showed significant and concentration-dependent antioxidant and free radical scavenging activities. Consequently, the Sugiol exerted lipid peroxidation inhibitory effect by 76.5% as compared to α±-tocopherol (80.13%) and butylated hydroxyanisole (76.59%). In addition, the Sugiol had significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals in a concentration-dependent manner by 78.83%, 72.42%, 72.99% and 85.04%, when compared to the standard compound ascorbic acid (81.69%, 74.62%, 73.00% and 73.79%) and α±-tocopherol/butylated hydroxyanisole (84.09%, 78.61%, 74.45% and 70.02%), respectively[1] |
| 别名 | 10-Deoxoxanthoperol |
| 分子量 | 300.44 |
| 分子式 | C20H28O2 |
| CAS No. | 511-05-7 |
存储
store at low temperture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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