Mitraphylline
作者：齐岳
发布时间：2023-09-06
09:05:29
点击数：
产品名称：Mitraphylline
产品描述：
| 植物来源 | 天然产物 > 茜草科 > 钩藤属 |
| 结构类型 | 天然产物 > 生物碱 |
| 产品描述 | Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils. |
| 体外活性 | The alkaloids of Uncaria tomentosa micropropagated plantlets and root cultures were isolated and identified by NMR and mass spectrometry. Plantlets yielded pteropodine (1), isopteropodine (2), Mitraphylline (3), isoMitraphylline (4), uncarine F (5), speciophylline (6), rhynchophylline (7) and isorhynchophylline (8). In plantlets growing under continuous light, tetracyclic alkaloids 7 and 8 decreased from 20 ± 1.8 at 2 months to 2.2 ± 0.33 mg/g dry wt at 6 months, while the pentacyclic alkaloids 1-4 increased from 7.7 ± 1.4 to 15 ± 0.05 mg/g dry wt, supporting their biogenetic conversion. Micropropagated plantlets produced four times more alkaloids (27.6 ± 3.1 mg/g dry wt) than greenhouse plants. |
| 别名 | 帽柱木菲碱, 帽柱叶碱 |
| 分子量 | 368.43 |
| 分子式 | C21H24N2O4 |
| CAS No. | 509-80-8 |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 6.76 mg/mL (18.35 mM),Need ultrasonic
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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