Oenothein B
作者：齐岳
发布时间：2023-08-30
09:00:21
点击数：
产品名称：Oenothein B
产品描述：
| 产品描述 | Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties. |
| 体外活性 | Oenothein B (15-45 µM; 24 hours) not only increased the level of intracellular reactive oxygen species (ROS) but also induced the upregulation of intracellular apoptotic triggers (cleavage caspase-3, PARP, cytochrome c level in the cytosol, Bax). Oenothein B (15-45 µM; 12-72 hours) had a dose- and time-dependent inhibition rate effect on A549 cells exposure. Oenothein B (15-45 µM; 24 hours) effectively inhibited the proliferation of A549 cells by inducing apoptosis and arresting cells at the G1 stage[3]. |
| 体内活性 | In ICR mice, Oenothein B (100-300 mg/kg; p.o.) reduced neuroinflammation in the brain during systemic inflammation[2]. |
| 分子量 | 1569.08 |
| 分子式 | C68H48O44 |
| CAS No. | 104987-36-2 |
存储
| Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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