Caspase-3 Inhibitor I
作者：齐岳
发布时间：2023-08-29
13:40:53
点击数：
产品名称：Caspase-3 Inhibitor I
产品描述：
| 产品描述 | Caspase-3 Inhibitor I is a specific inhibitor of Caspase-3. |
| 体外活性 | Pretreatment with the caspase-3 inhibitor Ac-DEVD-CHO or antioxidant NAC blocked SLNT-induced apoptosis[1]. The apoptosis of SP2/0 cells was blocked by a pan-caspase inhibitor Z-VAD-FMK and caspase-3 inhibitor Ac-DEVD-CHO[2]. |
| 体内活性 | Compared with model group, in CI group, the concentrations of serum BUN were decreased significantly at all time points after operation and those of Cr were decreased significantly at 6 hours, then restored to those of the sham group at 12 hours and 24 hours; the concentrations of serum TNF-α, IL-6 were decreased and those of IL-10 elevated significantly at all time points[3]. |
| 别名 | Ac-DEVD-CHO acetate (169332-60-9 free base), 乙酰基-天冬氨酰-谷氨酰-缬氨酰-天冬氨醛, N-acetyl-asp-glu-val-asp-al |
| 分子量 | 562.52 |
| 分子式 | C22H34N4O13 |
| CAS No. | TQ0146L |
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
H2O: 40 mg/mL (79.61 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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