Scyliorhinin II acetate
作者：齐岳
发布时间：2023-06-26
09:06:35
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产品名称：Scyliorhinin II acetate
产品描述：
Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.
Scyliorhinin II acetate has little effect on NK1 and NK2 receptors. The Ki values for NK1/NK3 and NK2/NK3 are 176 and 200, respectively[2].
In mice, Scyliorhinin II acetate(i.c.v.) produced potent and dose-related reciprocal hindlimb scratching about equipotently (ED50 = 0.08 nmol)[1].
C79H123N21O28S3
1911.14
Scyliorhinin II acetate
[1]Buck SH, et al. The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors. Eur J Pharmacol. 1987 Nov 24;144(1):109-11.[2]Raffa RB, et al. Scyliorhinin-I and -II induce reciprocal hindlimb scratching in mice: differentiation of spinal and supraspinal neurokinin receptors in vivo. Neurosci Lett. 1993 Aug 6;158(1):87-91.
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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