PAR-4 Agonist Peptide, amide TFA
作者：齐岳
发布时间：2023-06-26
09:06:18
点击数：
产品名称：PAR-4 Agonist Peptide, amide TFA
产品描述：
PAR-4 Agonist Peptide, amide TFA is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
SCID mice have a significantly greater abdominal response to colorectal distension (CRD) at the distension levels of 0.04 to 0.1 mL increasing the intensity of EMG response by 384% to 132%, respectively (P<0.01; P<0.01; P<0.01; P<0.001) when compared with their BALB/cBy controls. PAR-4 activation effectively reverses this hypersensitivity (P<0.01, P<0.05; P<0.05; P<0.05)[1].
1228078-65-6
C36H49F3N8O9
794.83
PAR-4-AP (TFA);AY-NH2 (TFA);PAR-4 Agonist Peptide, amide TFA
[1]Annaházi A, et al. Proteinase-activated receptor-4 evoked colorectal analgesia in mice: an endogenously activatedfeed-back loop in visceral inflammatory pain. Neurogastroenterol Motil. 2012 Jan;24(1):76-85, e13.
H2O:100 mg/mL (125.81 mM),Need ultrasonic
DMSO:250 mg/mL (314.54 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO:250 mg/mL (314.54 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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