活性氧α-Tocotrienol,58864-81-6
产品名称:活性氧α-Tocotrienol,58864-81-6
产品描述:
产品名称:活性氧α-Tocotrienol,58864-81-6
产地:西安
规格:1mg 5mg 10mg
纯度:99%
用途:仅用于科研
状态:固体/粉末
储藏条件:冷藏-20℃
温馨提示:仅用于科研,不能用于人体实验!
说明:提供使用说明,核磁图谱,包装,价格,产地,制备方法,应用,稳定性,溶解度,简单合成等各种信息
α-Tocotrienol is an antioxidant and a form of vitamin E that has been found in rice bran and has neuroprotective properties.1,2,3,4 It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 (Item No. 82220), or L-buthionine-(S,R)-sulfoximine (BSO; Item No. 14484) in rat striatal cultures when used at concentrations ranging from 0.1 to 10 µM.2 Cytosolic microinjection of α-tocotrienol prevents glutamate-induced cell death and phosphorylation of 12-lipoxygenase (12-LO) in HT4 neurons.3 It reduces glutamate-induced cytosolic and mitochondrial production of reactive oxygen species (ROS), accumulation of N-terminally truncated Bcl-xL (ΔN-Bcl-xL), and cell death in primary rat hippocampal neurons.4 α-Tocotrienol (50 mg/kg) reduces infarct size in a spontaneously hypertensive rat model of stroke induced by tandem right common carotid artery and middle cerebral artery occlusion.3 [Matreya, LLC. Catalog No. 2109]
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